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bacteria:t3e:xopd [2020/07/08 18:25] rkoebnik |
bacteria:t3e:xopd [2020/07/08 18:27] (current) rkoebnik [Biological function] |
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=== (Experimental) evidence for being a T3E === | === (Experimental) evidence for being a T3E === | ||
- | XopD is a desumoylating enzyme with strict specificity for its plant small ubiquitin-like modifier (SUMO) substrates (Chosed //et al//., 2007). C-terminus of XopD (amino acids 322–520) shares primary sequence similarity with the C48 family of cysteine peptidases (Rawlings //et al//., 2006). In the XopD polypeptide, | + | XopD is a desumoylating enzyme with strict specificity for its plant small ubiquitin-like modifier (SUMO) substrates (Chosed //et al//., 2007). C-terminus of XopD (amino acids 322–520) shares primary sequence similarity with the C48 family of cysteine peptidases (Rawlings //et al//., 2006). In the XopD polypeptide, |
- | Besides C-terminal SUMO protease domain (Chosed | + | Besides C-terminal SUMO protease domain (Hotson |
=== Regulation === | === Regulation === | ||
- | The //xopD// gene expression is induced in a //hrpG//- and // | + | The //xopD// gene expression is induced in a //hrpG//- and // |
=== Phenotypes === | === Phenotypes === | ||
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=== Localization === | === Localization === | ||
- | XopD localizes to subnuclear foci. The N terminus of XopD is required for targeting the effector to the plant nucleus; C-terminal domain encodes a Cys protease that cleaves SUMO-conjugated proteins (Hotson //et al//., 2003; Kim //et al//., 2008)). | + | XopD localizes to subnuclear foci. The N terminus of XopD is required for targeting the effector to the plant nucleus; C-terminal domain encodes a Cys protease that cleaves SUMO-conjugated proteins (Hotson //et al//., 2003; Kim //et al//., 2008). |
=== Enzymatic function === | === Enzymatic function === | ||
- | Peptidase, isopeptidase or desumoylating enzyme (Hotson//et al//., 2003). | + | Peptidase, isopeptidase or desumoylating enzyme (Hotson// et al//., 2003). |
=== Interaction partners === | === Interaction partners === | ||