This shows you the differences between two versions of the page.
Both sides previous revision Previous revision Next revision | Previous revision | ||
bacteria:t3e:xopac [2020/08/09 18:17] rkoebnik |
— (current) | ||
---|---|---|---|
Line 1: | Line 1: | ||
- | ====== XopAC ====== | ||
- | |||
- | Author: [[https:// | ||
- | Internal reviewer: FIXME \\ | ||
- | Expert reviewer: FIXME | ||
- | |||
- | Class: XopAC\\ | ||
- | Family: XopAC\\ | ||
- | Prototype: XopAC (// | ||
- | RefSeq ID: [[https:// | ||
- | 3D structure: Unknown | ||
- | |||
- | ===== Biological function ===== | ||
- | |||
- | === How discovered? === | ||
- | |||
- | XopAC/AvrAC was identified as a putative type III effector because of the presence of seven prokaryotic-type leucine-rich repeats in its C-terminal domain and a PIP-box motif in //xopAC// promoter suggestive of a // | ||
- | === (Experimental) evidence for being a T3E === | ||
- | |||
- | The first XopAC< | ||
- | === Regulation === | ||
- | |||
- | //xopAC// promoters possess a PIP-box motif (Xu //et al//., 2008). Expression of //xopAC// is induced in // | ||
- | === Phenotypes === | ||
- | |||
- | * //xopAC//, also named //avrAC//, confers avirulence to // | ||
- | * // | ||
- | * // | ||
- | * XopAC inhibits BIK1 kinase activity and blocks flg22-induced PTI responses (Feng //et al//., 2012). | ||
- | * XopAC was found to be associated with variations in disease symptoms when testing a set of 45 //Xcc//// //strains on two // | ||
- | * Mutagenesis of type III effectors in // | ||
- | * When heterologously expressed in virulent //Ralstonia solanacearum// | ||
- | * Transgenic expression of // | ||
- | |||
- | === Localization === | ||
- | |||
- | XopAC was localized to the plasma membrane upon // | ||
- | |||
- | === Enzymatic function === | ||
- | |||
- | XopAC presents an uridylyl transferase activity dependent on residue H< | ||
- | |||
- | === Interaction partners === | ||
- | |||
- | Nine // | ||
- | |||
- | ===== Conservation ===== | ||
- | |||
- | === In xanthomonads === | ||
- | |||
- | xopAC is present in many //Xcc// strains as well as several // | ||
- | |||
- | === In other plant pathogens/ | ||
- | |||
- | No. | ||
- | |||
- | ===== References ===== | ||
- | |||
- | Cerutti A, Jauneau A, Auriac M-C, Lauber E, Martinez Y, Chiarenza S, Leonhardt N, Berthomé R, Noël LD (2017). Immunity at cauliflower hydathodes controls infection by // | ||
- | |||
- | Feng F, Yang F, Rong W, Wu X, Zhang J, Chen S, He C, Zhou JM (2012). A // | ||
- | |||
- | Guy E, Genissel A, Hajri A, Chabannes M, David P, Carrère S, Lautier M, Roux B, Boureau T, Arlat M, Poussier S, Noël LD (2013a). Natural genetic variation of // | ||
- | |||
- | Guy E, Lautier M, Chabannes M, Roux B, Lauber E, Arlat M, Noël LD (2013b). // | ||
- | |||
- | Wang G, Roux B, Feng F, Guy E, Li L, Li N, Zhang X, Lautier M, Jardinaud MF, Chabannes M, Arlat M, Chen S, He C, Noël LD, J.M. Zhou JM (2015). The decoy substrate of a pathogen effector and a pseudokinase specify pathogen-induced modified-self recognition and immunity in plants. Cell Host Microbe 18: 285-295. DOI: [[https:// | ||
- | |||
- | Xu RQ, Blanvillain S, Feng JX, Jiang BL, Li XZ, Wei HY, Kroj T, Lauber E, Roby D, Chen B, He YQ, Lu GT, Tang DJ, Vasse J, Arlat M, Tang JL (2008). AvrAC< | ||