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bacteria:t3e:xopaj [2020/09/29 22:21] lindsay.triplett_ct.gov |
bacteria:t3e:xopaj [2022/06/22 14:01] (current) rkoebnik [Biological function] |
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Authors: [[https:// | Authors: [[https:// | ||
Internal reviewer: [[https:// | Internal reviewer: [[https:// | ||
- | Expert reviewer: Lindsay Triplett | + | Expert reviewer: |
+ | |||
+ | Class: XopAJ\\ | ||
+ | Family: XopAJ\\ | ||
+ | Prototype: XopAJ (// | ||
+ | RefSeq ID: [[https:// | ||
+ | Synonym: AvrRxo1\\ | ||
+ | 3D structure: [[https:// | ||
+ | ====== XopAJ ====== | ||
+ | |||
+ | Authors: [[https:// | ||
+ | Internal reviewer: [[https:// | ||
+ | Expert reviewer: [[https:// | ||
Class: XopAJ\\ | Class: XopAJ\\ | ||
Line 37: | Line 49: | ||
* AvrRxo1 is a kinase that converts NAD to 3' | * AvrRxo1 is a kinase that converts NAD to 3' | ||
* AvrRxo1 targets the cysteine protease RD21A, which is required for drought-induced immunity (Liu //et al.//, 2020). | * AvrRxo1 targets the cysteine protease RD21A, which is required for drought-induced immunity (Liu //et al.//, 2020). | ||
+ | * AvrRxo1 enhances // | ||
=== Localization === | === Localization === | ||
Line 44: | Line 57: | ||
=== Enzymatic function === | === Enzymatic function === | ||
- | AvrRxo1 has a T4 polynucleotide kinase domain (Han //et al.//, 2015; Wu //et al//., 2015). | + | AvrRxo1 has a T4 polynucleotide kinase domain (Han //et al.//, 2015; Wu //et al//., 2015). AvrRxo1 is an ATP-dependent protease (Liu //et al.//, 2022). |
AvrRxo1 is a phosphotransferase that produces two novel metabolites by phosphorylating nicotinamide/ | AvrRxo1 is a phosphotransferase that produces two novel metabolites by phosphorylating nicotinamide/ | ||
- | AvrRxo1 phosphorylates NAD //in planta//, and its kinase catalytic sites are necessary for toxicity, suppression of PAMP-triggered immunity, and activation of Rxo1-mediated resistance (Shidore //et al.//, 2017). In a metabolomic profile, 3' | + | AvrRxo1 phosphorylates NAD //in planta//, and its kinase catalytic sites are necessary for toxicity, suppression of PAMP-triggered immunity, and activation of Rxo1-mediated resistance (Shidore //et al.//, 2017). In a metabolomic profile, 3' |
=== Interaction partners === | === Interaction partners === | ||
Line 57: | Line 70: | ||
AvrRxo1 interacts with the // | AvrRxo1 interacts with the // | ||
+ | |||
+ | AvrRxo1 interacts with OsPDX1.2 in a yeast two-hybrid assay and in planta, as assessed by split YFP and coIP assays (Liu //et al.//, 2022). | ||
===== Conservation ===== | ===== Conservation ===== | ||
Line 72: | Line 87: | ||
Yes (// | Yes (// | ||
- | Homologs of the // | + | Homologs of the // |
+ | |||
+ | ===== Conservation ===== | ||
+ | |||
+ | === In xanthomonads === | ||
+ | |||
+ | Yes (e.g. //X. alfalfae//, //X. axonopodis//, | ||
+ | |||
+ | AvrRxo1 appears to be widely conserved in Asian strains of // | ||
+ | |||
+ | AvrRxo1 is conserved in nearly all strains of //X. euvesicatoria//, | ||
+ | |||
+ | === In other plant pathogens/ | ||
+ | |||
+ | Yes (// | ||
+ | |||
+ | Homologs of the // | ||
===== References ===== | ===== References ===== | ||
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Bahadur RP, Basak J (2014). Molecular modeling of protein-protein interaction to decipher the structural mechanism of nonhost resistance in rice. J. Biomol. Struct. Dyn. 32: 669-681. DOI: [[https:// | Bahadur RP, Basak J (2014). Molecular modeling of protein-protein interaction to decipher the structural mechanism of nonhost resistance in rice. J. Biomol. Struct. Dyn. 32: 669-681. DOI: [[https:// | ||
- | Han Q, Zhou C, Wu S, Liu Y, Triplett L, Miao J, Tokuhisa J, Deblais L, Robinson H, Leach JE, Li J, Zhao B (2015). Crystal structure of // | + | Han Q, Zhou C, Wu S, Liu Y, Triplett L, Miao J, Tokuhisa J, Deblais L, Robinson H, Leach JE, Li J, Zhao B (2015). Crystal structure of // |
Liu H, Chang Q, Feng W, Zhang B, Wu T, Li N, Yao F, Ding X, Chu Z (2014). Domain dissection of AvrRxo1 for suppressor, avirulence and cytotoxicity functions. PLoS One 9: e113875. DOI: [[https:// | Liu H, Chang Q, Feng W, Zhang B, Wu T, Li N, Yao F, Ding X, Chu Z (2014). Domain dissection of AvrRxo1 for suppressor, avirulence and cytotoxicity functions. PLoS One 9: e113875. DOI: [[https:// | ||
- | Liu Y, Wang K, Cheng Q, Kong D, Zhang X, Wang Z, Wang Q, Qi X, Yan J, Chu J, Ling H, Li Q, Miao J, Zhao B (2020). Cysteine protease RD21A regulated by E3 ligase SINAT4 is required for drought-induced resistance to // | + | Liu H, Lu C, Li Y, Wu T, Zhang B, Liu B, Feng W, Xu Q, Dong H, He S, Chu Z, Ding X (2022). The bacterial effector AvrRxo1 inhibits vitamin B6 biosynthesis to promote infection in rice. Plant Commun. 3: 100324. DOI: [[https:// |
+ | |||
+ | Liu Y, Wang K, Cheng Q, Kong D, Zhang X, Wang Z, Wang Q, Qi X, Yan J, Chu J, Ling H, Li Q, Miao J, Zhao B (2020). Cysteine protease RD21A regulated by E3 ligase SINAT4 is required for drought-induced resistance to // | ||
- | Popov G, Fraiture M, Brunner F, Sessa G (2016). Multiple // | + | Popov G, Fraiture M, Brunner F, Sessa G (2016). Multiple // |
- | Salomon D, Dar D, Sreeramulu S, Sessa G (2011). Expression of // | + | Salomon D, Dar D, Sreeramulu S, Sessa G (2011). Expression of // |
Schuebel F, Rocker A, Edelmann D, Schessner J, Brieke C, Meinhart A (2016). 3' | Schuebel F, Rocker A, Edelmann D, Schessner J, Brieke C, Meinhart A (2016). 3' | ||
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Triplett LR, Shidore T, Long J, Miao J, Wu S, Han Q, Zhou C, Ishihara H, Li J, Zhao B, Leach JE (2016). AvrRxo1 Is a bifunctional type III secreted effector and toxin-antitoxin system component with homologs in diverse environmental contexts. PLoS One 11: e0158856. DOI: [[https:// | Triplett LR, Shidore T, Long J, Miao J, Wu S, Han Q, Zhou C, Ishihara H, Li J, Zhao B, Leach JE (2016). AvrRxo1 Is a bifunctional type III secreted effector and toxin-antitoxin system component with homologs in diverse environmental contexts. PLoS One 11: e0158856. DOI: [[https:// | ||
- | Wonni I, Cottyn B, Detemmerman L, Dao S, Ouedraogo L, Sarra S, Tekete C, Poussier S, Corral R, Triplett L, Koita O, Koebnik R, Leach J, Szurek B, Maes M, Verdier V (2014). Analysis of // | + | Wonni I, Cottyn B, Detemmerman L, Dao S, Ouedraogo L, Sarra S, Tekete C, Poussier S, Corral R, Triplett L, Koita O, Koebnik R, Leach J, Szurek B, Maes M, Verdier V (2014). Analysis of // |
- | Wu S (2015). Structural and functional characterization of a // | + | Wu S (2015). Structural and functional characterization of a // |
- | Xie XW, Yu J, Xu JL, Zhou YL, Li ZK (2007). Introduction of a non-host gene // | + | Xie XW, Yu J, Xu JL, Zhou YL, Li ZK (2007). Introduction of a non-host gene //Rxo1// cloned from maize resistant to rice bacterial leaf streak into rice varieties. Sheng Wu Gong Cheng Xue Bao [Chinese J. Biotechnol.] 23: 607-611. DOI: [[https:// |
- | Zhao B, Ardales EY, Raymundo A, Bai J, Trick HN, Leach JE, Hulbert SH (2004). The // | + | Zhao B, Ardales EY, Raymundo A, Bai J, Trick HN, Leach JE, Hulbert SH (2004). The //avrRxo1// gene from the rice pathogen // |
Zhao B, Lin X, Poland J, Trick H, Leach J, Hulbert S (2005). A maize resistance gene functions against bacterial streak disease in rice. Proc. Natl. Acad. Sci. USA 102: 15383-15388. DOI: [[https:// | Zhao B, Lin X, Poland J, Trick H, Leach J, Hulbert S (2005). A maize resistance gene functions against bacterial streak disease in rice. Proc. Natl. Acad. Sci. USA 102: 15383-15388. DOI: [[https:// | ||