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--- bacteria:t3e:xope3 [2020/09/21 10:35]
rkoebnik [References]
+++ bacteria:t3e:xope3 [2020/09/21 10:37] (current)
rkoebnik [Biological function]
@@ Line 34: / Line 34: @@
 === Interaction partners ===
-In //X. citri //subsp. //citri //A306 the gene coding for XopE3 is in a region hypothesized to be a genomic island (Moreira //et al.//, 2010). This region or parts of it are conserved in many Xanthomonas strains, as shown by a genomic neighborhood search in the Integrated Microbial Genomes platform. In particular, in this search gene XAC3225 is nearly always adjacent to XAC3224 (//xopE3//), suggesting that the protein coded by XAC3225 is an interaction partner of XopE3. Moreira //et al.// (2010) commented on this as follows: "Next to //xopE3// (XAC3224) we find gene XAC3225, whose product is annotated as tranglycosylase mltB. This gene has strong similarity (e-value 10<sup>-133</sup> , 100% coverage) to //hopAJ1// from //P. syringae// pv. //tomato// strain DC3000, where it is annotated as a T3SS helper protein. Although the //hopAJ1// gene is not itself a T3SS substrate, it contributes to effector translocation (Oh //et al.//, 2007). A mutant with a deletion of XAC3225 has reduced ability to cause canker (mutant phenotypes include a reduction in water soaking, hyperplasia, and necrosis compared to wild type) (Laia //et al.//, 2009)".
+In //X. citri //subsp. //citri //A306 the gene coding for XopE3 is in a region hypothesized to be a genomic island (Moreira //et al.//, 2010). This region or parts of it are conserved in many Xanthomonas strains, as shown by a genomic neighborhood search in the Integrated Microbial Genomes platform. In particular, in this search gene XAC3225 is nearly always adjacent to XAC3224 (//xopE3//), suggesting that the protein coded by XAC3225 is an interaction partner of XopE3. Moreira //et al.// (2010) commented on this as follows: "Next to //xopE3// (XAC3224) we find gene XAC3225, whose product is annotated as tranglycosylase //mltB//. This gene has strong similarity (e-value 10<sup>-133</sup>  , 100% coverage) to //hopAJ1// from //P. syringae// pv. //tomato// strain DC3000, where it is annotated as a T3SS helper protein. Although the //hopAJ1// gene is not itself a T3SS substrate, it contributes to effector translocation (Oh //et al.//, 2007). A mutant with a deletion of XAC3225 has reduced ability to cause canker (mutant phenotypes include a reduction in water soaking, hyperplasia, and necrosis compared to wild type) (Laia //et al.//, 2009)".
 ===== Conservation =====

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