This shows you the differences between two versions of the page.
Both sides previous revision Previous revision Next revision | Previous revision Next revision Both sides next revision | ||
bacteria:t3e:xopi [2020/06/30 22:27] irodrigues |
bacteria:t3e:xopi [2020/07/08 18:46] rkoebnik [XopI] |
||
---|---|---|---|
Line 1: | Line 1: | ||
====== XopI ====== | ====== XopI ====== | ||
- | Author: Trainees from the EuroXanth | + | Author: |
Internal reviewer: Isabel Rodrigues\\ | Internal reviewer: Isabel Rodrigues\\ | ||
Expert reviewer: FIXME | Expert reviewer: FIXME | ||
Class: XopI\\ | Class: XopI\\ | ||
- | Family: | + | Family: |
- | Prototype: (// | + | Prototype: (// |
RefSeq ID: [[https:// | RefSeq ID: [[https:// | ||
3D structure: Unknown | 3D structure: Unknown | ||
Line 27: | Line 27: | ||
=== Localization === | === Localization === | ||
- | XopI is translocated by the 85*Δ// | + | XopI is translocated by the 85*Δ// |
=== Enzymatic function === | === Enzymatic function === | ||
Line 33: | Line 33: | ||
=== Interaction partners === | === Interaction partners === | ||
- | XopR and XopS belong to //Xcv// translocation class A, comprising T3Es whose translocation into plant cells is completely dependent on HpaB, whereas XopB, XopG, XopI, XopK, XopM and XopV were assigned to class B, because they are still translocated in the absence of HpaB (Büttner //et al.//, 2006). Both new class A effectors lack homology to known proteins or motifs, so that their molecular function remains elusive. By contrast, the class B effectors comprise the putative enzyme XopG, a member of the HopH family | + | XopR and XopS belong to //Xcv// translocation class A, comprising T3Es whose translocation into plant cells is completely dependent on HpaB, whereas XopB, XopG, **XopI**, XopK, XopM and XopV were assigned to class B, because they are still translocated in the absence of HpaB (Büttner //et al.//, 2006). Both new class A effectors lack homology to known proteins or motifs, so that their molecular function remains elusive. By contrast, the class B effectors comprise the putative enzyme XopG, a member of the HopH family of putative zinc metalloproteases. Other effectors possess interesting features, for example XopI contains an F‐box motif typical for eukaryotic proteins playing a role in the ubiquitin‐26S proteasome system (UPS). The UPS controls protein stability in eukaryotes and appears to be a favorable target for many T3Es, for example members of the GALA family, which strongly contribute to the virulence of //R. solanacearum// |
===== Conservation ===== | ===== Conservation ===== | ||
Line 46: | Line 46: | ||
===== References ===== | ===== References ===== | ||
- | Nagel O, Bonas U (2018). The // | + | <font 10.5pt/ |
+ | |||
+ | Nagel O, Bonas U (2018). The // | ||
Salomon D, Dar D, Sreeramulu S, Sessa G (2011). Expression of // | Salomon D, Dar D, Sreeramulu S, Sessa G (2011). Expression of // | ||
Line 55: | Line 57: | ||
Üstün S, Börnke F (2014). Interactions of // | Üstün S, Börnke F (2014). Interactions of // | ||
+ | |||
+ | ===== Further reading ===== | ||
+ | |||
+ | Thieme F (2006). Genombasierte Identifizierung neuer potentieller Virulenzfaktoren von // | ||