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bacteria:t3e:xopp [2020/07/03 18:13] rkoebnik |
bacteria:t3e:xopp [2022/06/23 09:53] rkoebnik [Biological function] |
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Class: XopP\\ | Class: XopP\\ | ||
Family: XopP\\ | Family: XopP\\ | ||
- | Prototype: XopP (// | + | Prototype: XopP (// |
RefSeq ID: [[https:// | RefSeq ID: [[https:// | ||
3D structure: Unknown | 3D structure: Unknown | ||
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=== How discovered? === | === How discovered? === | ||
- | XopP was identified in a genetic screen, using a Tn// | + | XopP was identified in a genetic screen, using a Tn// |
=== (Experimental) evidence for being a T3E === | === (Experimental) evidence for being a T3E === | ||
Line 26: | Line 26: | ||
=== Phenotypes === | === Phenotypes === | ||
- | Roden //et al.// did not find significant growth defects of a //Xcv// Δ//xopP// mutant in susceptible pepper and tomato leaves (Roden et al., 2004). | + | * Roden //et al.// did not find significant growth defects of a // |
+ | * XopQ< | ||
+ | * XopP< | ||
+ | * // | ||
+ | * XopP inhibits the function of the host-plant exocyst complex by direct targeting of Exo70B, a subunit of the exocyst complex, which plays a significant role in plant immunity. XopP interferes with exocyst-dependent exocytosis, and can do this without activating a plant NLR (NOD-like receptor) that guards Exo70B in Arabidopsis. In this way, // | ||
- | XopQ< | ||
- | |||
- | XopP< | ||
=== Localization === | === Localization === | ||
- | XopP< | + | XopP< |
=== Enzymatic function === | === Enzymatic function === | ||
Line 40: | Line 42: | ||
=== Interaction partners === | === Interaction partners === | ||
- | XopP< | + | XopP< |
===== Conservation ===== | ===== Conservation ===== | ||
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Yes (//e.g.//, //Ralstonia solanacearum// | Yes (//e.g.//, //Ralstonia solanacearum// | ||
===== References ===== | ===== References ===== | ||
+ | |||
+ | Deb S, Ghosh P, Patel HK, Sonti RV (2020). Interaction of the // | ||
Furutani A, Takaoka M, Sanada H, Noguchi Y, Oku T, Tsuno K, Ochiai H, Tsuge S (2009). Identification of novel type III secretion effectors in // | Furutani A, Takaoka M, Sanada H, Noguchi Y, Oku T, Tsuno K, Ochiai H, Tsuge S (2009). Identification of novel type III secretion effectors in // | ||
Line 58: | Line 63: | ||
Liu Y, Long J, Shen D, Song C (2016). // | Liu Y, Long J, Shen D, Song C (2016). // | ||
+ | |||
+ | Michalopoulou VA, Mermigka G, Kotsaridis K, Mentzelopoulou A, Celie PHN, Moschou PN, Jones JDG, Sarris PF (2022). The host exocyst complex is targeted by a conserved bacterial type-III effector that promotes virulence. Plant Cell, in press. DOI: [[https:// | ||
Roden JA, Belt B, Ross JB, Tachibana T, Vargas J, Mudgett MB (2004). A genetic screen to isolate type III effectors translocated into pepper cells during // | Roden JA, Belt B, Ross JB, Tachibana T, Vargas J, Mudgett MB (2004). A genetic screen to isolate type III effectors translocated into pepper cells during // | ||