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bacteria:t3e:xopau [2020/05/15 16:19] jfpothier |
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- | ====== XopAU ====== | ||
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- | Author: Eran Bosis\\ | ||
- | Internal reviewer: FIXME \\ | ||
- | Expert reviewer: FIXME | ||
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- | Class: XopAU.\\ | ||
- | Family: XopAU\\ | ||
- | Prototype: XopAU (//X// // | ||
- | RefSeq ID: [[https:// | ||
- | 3D structure: Unknown | ||
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- | ===== Biological function ===== | ||
- | |||
- | === How discovered? === | ||
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- | XopAU was discovered using a machine-learning approach (Teper //et al//., 2016). | ||
- | === (Experimental) evidence for being a T3E === | ||
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- | XopAU fused to the AvrBs2 reporter, was shown to translocate into plant cells in an // | ||
- | === Regulation === | ||
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- | XopAU homologs were shown to contain the PIP-box motif in their promoter region (Tepper //et al.//, 2018). XopAU from //X. citri// was found to be regulated by HrpG and HrpX (Guo //et al.//, 2011). | ||
- | === Phenotypes === | ||
- | |||
- | // | ||
- | === Localization === | ||
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- | Unknown. | ||
- | |||
- | === Enzymatic function === | ||
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- | XopAU is an active protein kinase //in vitro// (Tepper //et al//., 2018). | ||
- | === Interaction partners === | ||
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- | XopAU was shown to interact with tomato MAPKK MKK2 and MAP kinases. Co-expression of XopAU and MKK2 in yeast caused a growth-inhibition phenotype. XopAU was shown to phosphorylate MKK2 //in vitro// and to promote phosphorylation of MKK2 at multiple sites //in planta// (Tepper //et al//., 2018). XopAU was shown to interact with tomato 14-3-3 (TFT) proteins (Dubrow //et al//., 2018). | ||
- | ===== Conservation ===== | ||
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- | === In xanthomonads === | ||
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- | Yes (//e.g.//, //X. fuscans, X. citri, X. oryzae, X. fragariae// | ||
- | === In other plant pathogens/ | ||
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- | Yes (// | ||
- | ===== References ===== | ||
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- | Dubrow Z, Sunitha S, Kim JG, Aakre CD, Girija AM, Sobol G, Teper D, Chen YC, Ozbaki-Yagan N, Vance H, Sessa G, Mudgett MB (2018). Tomato 14-3-3 proteins are required for //Xv3// disease resistance and interact with a subset of // | ||
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- | Guo Y, Figueiredo F, Jones J, Wang N (2011). HrpG and HrpX play global roles in coordinating different virulence traits of // | ||
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- | Teper D, Burstein D, Salomon D, Gershovitz M, Pupko T, Sessa G (2016). Identification of novel // | ||
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- | Teper D, Girija AM, Bosis E, Popov G, Savidor A, Sessa G (2018). The // | ||