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bacteria:t3e:xopl [2020/07/07 12:01] rkoebnik [XopL] |
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- | ====== XopL ====== | ||
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- | Author: [[https:// | ||
- | Internal reviewer: [[https:// | ||
- | Expert reviewer: FIXME | ||
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- | Class: XopL\\ | ||
- | Family: XopL\\ | ||
- | Prototype: XopL< | ||
- | RefSeq ID: [[https:// | ||
- | Examples of other sequences: XopL< | ||
- | 3D structure: | ||
- | [[https:// | ||
- | ). Full-length XopL< | ||
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- | ===== Biological function ===== | ||
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- | === How discovered? === | ||
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- | XopL was first identified in //X. campestris// | ||
- | === (Experimental) evidence for being a T3E === | ||
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- | Using an AvrBs1 reporter fusion, XopL< | ||
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- | XopL< | ||
- | === Regulation === | ||
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- | The //xopL// < | ||
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- | qRT-PCR revealed that transcript levels of 15 out of 18 tested non-TAL effector genes (as well as the regulatory genes //hrpG// and //hrpX//), including //xopL//, were significantly reduced in the // | ||
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- | The expression of //xopL// < | ||
- | === Phenotypes === | ||
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- | * XopL< | ||
- | * In contrast, XopL< | ||
- | * XopL< | ||
- | * XopL< | ||
- | * Transient expression of XopL, led to a nearly complete elimination of stromules and the relocation of plastids to the nucleus and further characterization of XopL revealed that the E3 ligase activity is essential for two plastid phenotypes (Erickson //et al//., 2016). | ||
- | * XopL< | ||
- | * XopL< | ||
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- | === Localization === | ||
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- | Possibly plasma membrane. The transiently expressed XopL< | ||
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- | === Enzymatic function === | ||
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- | E3 ubiquitin ligase activity (Singer //et al//., 2013). | ||
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- | === Interaction partners === | ||
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- | Unknown. | ||
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- | ===== Conservation ===== | ||
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- | === In xanthomonads === | ||
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- | Yes in // | ||
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- | === In other plant pathogens/ | ||
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- | No. | ||
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- | ===== References ===== | ||
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- | Adlung N (2016). Charakterisierung der Avirulenzaktivität von XopQ und Identifizierung möglicher Interaktoren von XopL aus // | ||
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- | Erickson JL, Adlung N, Lampe C, Bonas U, Schattat MH (2018). The // | ||
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- | Jiang W, Jiang BL, Xu RQ, Huang JD, Wei HY, Jiang GF, Cen WJ, Liu J, Ge YY, Li GH, Su LL, Hang XH, Tang DJ, Lu GT, Feng JX, He YQ, Tang JL (2009). Identification of six type III effector genes with the PIP box in // | ||
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- | Liu Y, Long J, Shen D, Song C (2016). // | ||
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- | Popov G, Fraiture M, Brunner F, Sessa G (2016). Multiple // | ||
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- | Singer AU, Schulze S, Skarina T, Xu X, Cui H, Eschen-Lippold L, Egler M, Srikumar T, Raught B, Lee J, Scheel D, Savchenko A, Bonas U (2013). A pathogen type III effector with a novel E3 ubiquitin ligase architecture. PLoS Pathog. 9: e1003121. DOI: [[https:// | ||
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- | Soni M, Mondal KK. (2017). // | ||
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- | Yan X, Tao J, Luo HL, Tan LT, Rong W, Li HP, He CZ (2019). A type III effector XopL< | ||