This is an old revision of the document!
Author: Yael Helman
Internal reviewer: Monika Kałużna
Expert reviewer:
Class: XopAW
Family: XopAW
Prototype: XopAW (XCV3093; Xanthomonas euvesicatoria pv. euvesicatoria aka Xanthomonas campestris pv. vescicatoria; strain 85-10)
RefSeq ID: CAJ24824.1 (221 aa)
3D structure: Unknown
XopAW (XCV3093 in X. euvesicatoria 85-10 (was discovered using a machine-learning approach (Teper et al., 2016).
XopAW fused to the AvrBs2 reporter, was shown to translocate into plant cells in an hrpF-dependent manner (Teper et al., 2016).
Unknown.
A Xanthomonas euvesicatoria 85-10 mutant defective in xopAW did not exhibit reduced virulence symptoms when inoculated on leaves of susceptible pepper plants, relative to wild-type 85-10 (Teper et al., 2016). Additionally, expression in Arabidopsis mesophyll protoplasts did not lead to suppression of the PTI-associated responses induced by the bacterial peptide flg22 (Popov et al., 2018).
Unknown.
XopAW contains a canonical EF-hand calcium-binding motif and can potentially interfere with host calcium signaling (Teper et al., 2016).
Unknown.
Yes (e.g., X. perforans, X. axonopodis, X. citri, X. arboricola, X. phaseoli, X. campestris, X. sacchari, X. hyacinthi).
In other plant pathogens/symbionts
Yes (e.g., Ralstonia solanacearum, Acidovorax avenae, Pseudomonas syringae, Rhizobium) (Teper et al., 2016).
References
Popov G, Fraiture M, Brunner F, Sessa G (2018). Multiple Xanthomonas euvesicatoria type III effectors inhibit flg22-triggered immunity. Mol. Plant-Microbe Interact. 29(8):651-660. DOI: 10.1094/MPMI-07-16-0137-R.
Teper D, Burstein D, Salomon D, Gershovitz M, Pupko T, Sessa G (2016). Identification of novel Xanthomonas euvesicatoria type III effector proteins by a machine-learning approach. Mol. Plant Pathol. 17(3): 398-411. DOI: 10.1111/mpp.12288.