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Molecular Diagnosis and Diversity for Regulated Xanthomonas
Bacterial virulence factors
This DokuWiki is based upon work from COST Action CA16107 EuroXanth, supported by COST (European Cooperation in Science and Technology)
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Author: Vittoria Catara
Internal reviewer: Ralf Koebnik
Expert reviewer: 
Class: XopAK
Family: XopAK
Prototype: XopAK (Xanthomonas euvesicatoria pv. euvesicatoria aka Xanthomonas campestris pv. vescicatoria; strain 85-10)
RefSeq ID: CAJ25517.1 (485 aa)
3D structure: Unknown
XopAK was discovered using a machine-learning approach (Teper et al., 2016).
XopAK, fused to the AvrBs2 reporter, was shown to translocate into plant cells in an hrpF-dependent manner (Teper et al., 2016).
Unknown.
Disease severity, ion leakage, chlorophyll content of pepper plants inoculated with a mutant strain obtained by insertion mutagenesis of xopAK and in planta bacterial growth were not affected as compared to plants inoculated with the parent strain X. euvesicatoria pv. euvesicatoria (Xcv) 85-10 (Teper et al., 2016).
Unknown.
XopAK has been predicted to be a deamidase (Teper et al., 2016).
Unknown.
Yes (e.g., X. euvesicatoria, X. oryzae, X. citri, X. translucens (Teper et al., 2016; Barak et al., 2016)).
Yes (e.g., Ralstonia solanacearum (Teper et al., 2016), Pseudomonas syringae effector HopK1 (Li et al., 2014)).
Barak JD, Vancheva T, Lefeuvre P, Jones JB, Timilsina S, Minsavage GV, Vallad GE, Koebnik R (2016). Whole-genome sequences of Xanthomonas euvesicatoria strains clarify taxonomy and reveal a stepwise erosion of type 3 effectors. Front. Plant Sci. 7: 1805. DOI: 10.3389/fpls.2016.01805
Li G, Froehlich JE, Elowsky C, Msanne J, Ostosh AC, Zhang C, Awada T, Alfano JR (2014). Distinct Pseudomonas type-III effectors use a cleavable transit peptide to target chloroplasts. Plant J. 77: 310-321. DOI: 10.1111/tpj.12396
Teper D, Burstein D, Salomon D, Gershovitz M, Pupko T, Sessa G (2016). Identification of novel Xanthomonas euvesicatoria type III effector proteins by a machine‐learning approach. Mol. Plant Pathol. 17: 398-411. DOI: 10.1111/mpp.12288
